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John C's avatar
8hEdited

Great post, glad you're healthier now.

100% agree on the stomach stretching thing. But I would add we have TWO fullness systems in our body. The stomach stretching one is the fast/short term one (that tells us to STOP eating).

The other one is from fiber in our colon. A healthy microbiome releases short chain fatty acids SCFAs when it digests soluble fiber (mostly from veggies, beans and fruits). When the colon has less fiber in it, it releases less SCFAs. When your brain is getting SCFAs, they make you feel contented and not hungry. This slow/long term process tells you when its time to go find more food. The START eating signal.

Bariatric surgery spoofs the first pathway. Ozempic spoofs the second pathway.

The low fiber diet in the US (processed and fast foods are mostly zero fiber) means the second pathway is telling many Americans its 'time to eat' all the time. Ozempic turns that signal down/off.

Or you can just eat 20+ grams of soluble fiber a day, by eating plenty of veggies, beans and fruit.

I'm guessing that your diet contains a decent amount of whole foods and fiber, that is why you didn't 'need' ozempic. If you were eating more processed junk, your outcome might have been different.

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Thomas's avatar

I went from 85kg to 110kg with a side order of hypertension over the last five years with covid lockdowns and trying to get a business off the ground. Started liraglutide (not sure what it's called in the US) in Feb and lost around half of it since then. It's been life changing and aside from my doctor and my wife (also a doctor!), I couldn't care less about what other people think of it.

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